PubMedCrossRef 60. Desvaux M, Guedon E, Petitdemange H: Kinetics and metabolism of cellulose degradation at high substrate concentrations in steady-state continuous cultures of Clostridium cellulolyticum on a chemically defined medium. Appl Environ Microbiol 2001,67(9):3837–3845.PubMedCrossRef 61. Guedon E, Payot S, Desvaux M, Petitdemange H: Relationships between cellobiose catabolism, enzyme levels, and metabolic intermediates in Clostridium cellulolyticum grown in a synthetic medium. Biotechnol Bioeng 2000,67(3):327–335.PubMedCrossRef 62. Ben-Bassat A, Lamed R, Zeikus JG: Ethanol production by thermophilic bacteria: metabolic control of end product formation in Thermoanaerobium brockii. J Bacteriol 1981,146(1):192–199.PubMed

63. Levin DB, Islam R, Cicek N, Sparling R: Hydrogen production by Clostridium thermocellum 27405 from NSC 683864 research buy cellulosic biomass substrates. Int J Hydrogen Energy 2006,31(11):1496–1503.CrossRef 64. Strobel HJ, Caldwell FC, Dawson KA: Carbohydrate transport by the anaerobic thermophile Clostridium thermocellum LQRI. Appl Environ Microbiol 1995,61(11):4012–4015.PubMed 65. Zhang YH, Lynd LR: Regulation of cellulase synthesis in batch and continuous cultures of Clostridium thermocellum. J Bacteriol 2005,187(1):99–106.PubMedCrossRef 66. Girbal L, Soucaille P: Regulation Roscovitine molecular weight of Clostridium acetobutylicum metabolism as revealed by mixed-substrate steady-state continuous cultures: role of NADH/NAD ratio and ATP pool. J Bacteriol

1994,176(21):6433–6438.PubMed 67. Vasconcelos I, Girbal L, Soucaille P: Regulation of carbon and electron flow in Clostridium acetobutylicum

grown in chemostat culture at neutral pH on selleckchem mixtures of glucose and glycerol. J Bacteriol 1994,176(5):1443–1450.PubMed 68. Ml D, Guedon E, Petitdemange H: Metabolic flux in cellulose batch and cellulose-fed continuous cultures of Clostridium cellulolyticum in response to acidic environment. Microbiology 2001,147(6):1461–1471. 69. Lamed RJ, Lobos JH, Su TM: Effects of stirring and hydrogen on fermentation products of Clostridium thermocellum. Appl Environ Microbiol 1988,54(5):1216–1221.PubMed 70. Bothun GD, Knutson BL, Berberich Selleck C59 JA, Strobel HJ, Nokes SE: Metabolic selectivity and growth of Clostridium thermocellum in continuous culture under elevated hydrostatic pressure. Appl Microbiol Biotechnol 2004,65(2):149–157.PubMedCrossRef 71. Lamed R, Zeikus JG: Ethanol production by thermophilic bacteria: relationship between fermentation product yields of and catabolic enzyme activities in Clostridium thermocellum and Thermoanaerobium brockii. J Bacteriol 1980,144(2):569–578.PubMed 72. Rydzak T, Levin DB, Cicek N, Sparling R: End-product induced metabolic shifts in Clostridium thermocellum ATCC 27405. Appl Microbiol Biotechnol 2011,92(1):199–209.PubMedCrossRef 73. Sauer U, Eikmanns BJ: The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol Rev 2005,29(4):765–794.PubMedCrossRef 74.