CBA mice were no more resistant to MCW than C57BL/6 mice and for some MCMV strains appeared to control

infection less well than C57BL/6 mice. It is apparent that the previously described host resistance patterns of inbred mice and MCW are not consistently applicable for all MCMV strains.”
“OBJECTIVE: Atlantoaxial instability and odontoid invagination may occur in Down syndrome. The treatment of this lesion may require an odontoidectomy. In similar circumstances, a transoral procedure may be hampered by a macroglossia which is part of Down syndrome. In a situation occurring in an 11-year-old child affected by atloaxial instability and os odontoideum, the persistence of ventral compression after a previous atloaxial fixation induced us to perform an endoscopic endonasal odontoidectomy. We feel that this Gemcitabine price is an elective indication for endoscopic endonasal odontoidectomy.

CLINICAL PRESENTATION: An 11-year-old child, affected by Down syndrome, presented with progressive tetraparesis with severe superior diplegia. He was wheel chair bound. Recently, respiratory disturbances had

appeared.

INTERVENTION: The patient underwent an endoscopic endonasal odontoidectomy. The postoperative Course was uneventful, and the patient experienced improvement of the preoperative symptoms.

CONCLUSION: An endonasal technique is indicated for patients presenting with narrowness of the oral cavity, such as in the case reported, where the narrowness due to C59 wnt pediatric age and the macroglossia characteristic of Down syndrome hamper the transoral approach.”
“Sequencing of plant nuclear genomes reveals the widespread presence

of integrated viral sequences known as endogenous pararetroviruses (EPRVs). Banana is one of the three plant species known to harbor infectious EPRVs. Musa balbisiana carries integrated copies of Banana streak virus (BSV), which are infectious by releasing virions in interspecific hybrids. Here, we analyze the most organization of the EPRV of BSV Goldfinger (BSGfV) present in the wild diploid M. balbisiana cv. Pisang Klutuk Wulung (PKW) revealed by the study of Musa bacterial artificial chromosome resources and interspecific genetic cross. cv. PKW contains two similar EPRVs of BSGfV. Genotyping of these integrants and studies of their segregation pattern show an allelic insertion. Despite the fact that integrated BSGfV has undergone extensive rearrangement, both EPRVs contain the full-length viral genome. The high degree of sequence conservation between the integrated and episomal form of the virus indicates a recent integration event; however, only one allele is infectious. Analysis of BSGfV EPRV segregation among an F1 population from an interspecific genetic cross revealed that these EPRV sequences correspond to two alleles originating from a single integration event.