Table 4 illustrates the results of the multivariable logistic regression analyses examining the association between HIV testing uptake and log of HIV sexual risk, stratified by alcohol misuse. No relationships were identified among all participants, participants who drink alcohol and do not drink alcohol,

for both males and females. Table 4 Multivariable logistic Inhibitors,research,lifescience,medical regression analyses comparing HIV AGI-6780? screening uptake and log of HIV sexual risk score, stratified by alcohol use Univariable logistic regression and multivariable logistic regression analyses were conducted to assess the associations between HIV screening uptake and the intersection of sexual risk for HIV and alcohol misuse, as shown in Table 5. Univariable regression analyses revealed a strong relationship between HIV screening uptake, regretting ever having had sex while intoxicated,

and unsure if ever had sex while intoxicated among female drinkers. For male drinkers, a relationship Inhibitors,research,lifescience,medical was found between HIV screening Inhibitors,research,lifescience,medical uptake, sex while intoxicated and unsure if ever had sex while intoxicated. However, when adjusting for demographic characteristics in the multivariable logistic regression analyses, there were no relationships found for both males and females. Table 5 Univariable and multivariable logistic regression analyses comparing HIV screening uptake and the intersection of HIV sexual risk and alcohol misuse Reasons for accepting or declining HIV screening We examined factors related to reasons why participants accepted or declined HIV screening in the ED. Of those who agreed to screening, Inhibitors,research,lifescience,medical among women, 33.7% of drinkers and 25.5% of non-drinkers cited convenience as the most common reason why Inhibitors,research,lifescience,medical they accepted screening. Among men, 26.9% of drinkers and 32.1% of non-drinkers who accepted screening cited “because you asked” as the most common reason. Of the participants who declined screening, among women 51.7% of drinkers and 60% of non-drinkers, and among men 46.9% of drinkers and

63% of non-drinkers cited they did not believe they were at risk as the most common reason for not being screened. In examining the relationship Brefeldin_A between alcohol misuse and acceptance of screening, alcohol drinkers were just as likely as non-drinkers to say that they were not at risk for HIV among males (AOR 2.33 [0.89-6.11]) and females (AOR 0.83 [0.35-1.94]). Bingers were just as likely as non-bingers to say that they were not at risk for HIV among males (AOR 1.50 [0.62-3.64]) and females (AOR 1.03 [0.41-2.63]). Discussion Previous studies have noted a high prevalence of reported alcohol misuse, at-risk drinking and sexual risk for HIV among US ED patients [22,33,34,70,84,85]. Among participants in this study, too, there was a high prevalence of reported alcohol misuse and sexual risk for HIV.